The world's Oldest Handmade Musical Instrument

In all, researchers report finding the fragments of four flutes at two excavations in an area of southwestern Germany known as Swabia. Three of the sets of fragments were carved from mammoth ivory, but the real prize is a nearly complete flute hollowed out from the bone of a griffon vulture. That specimen was found in the Hohle Fels cave, just 28 inches (70 centimeters) away from the spot where the prehistoric Venus... was found.

When assembled, the vulture-bone flute is about eight and a half inches long (21.8 centimeters long) and boasts five finger holes. There are fine lines cut into the bone around the holes, suggesting that the flute's maker was calibrating the holes' placement to produce the nicest tones. One end of the flute is cut into a V shape, and the musician probably blew into that side of the flute. The researchers assume that an inch or two of the flute's far end is missing. LINK

You can listen to an MP3 of a replica flute being played.